Word: ldl
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...fingerprints of genes that predispose us to common kinds of diseases," Hood says. Based on the genetic profile, the computer will dispense some medical advice. It might say, "This individual has a tendency toward skin cancer and should avoid overexposure to the sun." Or: "He has insufficient LDL cholesterol receptors and a proclivity to obesity, so he should begin a high-fiber, low-fat diet at age 3." Explains Mark Skolnick, a geneticist at the University of Utah: "Once you can make a profile of a person's genetic predisposition to disease, medicine will finally become largely predictive and preventive...
...among those in this group who received aspirin along with the beta carotene capsules. The Harvard researchers have begun a trial in 45,000 postmenopausal women to see if a similar effect occurs in women. Scientists speculate that the antioxidant helps prevent those nasty oxygen- free radicals from transforming LDL, the bad form of cholesterol, into an even more menacing artery clogger...
Although they have no direct evidence,clinicians have seen oxidized LDL (LDL which hasabsorbed oxygen ions) devastate cells grown inpetri dishes, and they have suggested that itwould cause similar damage--perhaps even promotecancer growth--when shuttling through thecirculatory system of a human...
...Oxidized LDL could be lethal in another manneras well: by attracting "foam cells" ormacrophages, which cause plaque to grow on arterywalls, the molecule may lead directly to heartdisease...
Through its ability to scavenge free oxygenions, beta carotene could undermine the dangerousoperation of the LDL molecules and thus reducecancer and heart disease risk...