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After nearly two years of waiting, the results came out on Monday on the long-awaited heart drug Vytorin - and the news wasn't good. Vytorin's manufacturers, Merck and Schering-Plough, announced that while the drug reduced levels of LDL, or bad cholesterol, in a group of 750 patients, the medication, which has been on the market since 2004, had little effect on the buildup of plaque in the arteries, a harbinger of heart attack and stroke...
...many experts, the results were both a surprise and a warning. "The fact that the trial showed a huge LDL reduction, and that things were still going the wrong way [in terms of plaque buildup] is stunning," says Dr. Steven Nissen, chairman of cardiovascular medicine at the Cleveland Clinic and an outspoken critic of the delay in the release of the study results. "This study shows that it matters how you lower cholesterol, not just how much you lower cholesterol...
...days. The dreaded side-effects just aren't that common. For reasons never clear to the surgeons, new drugs catch on in waves; first it was Prozac, then Zoloft, now its Lexipro. All our patients were on Lipitor, now they're on Crestor. Treating numbers like bone density and LDL cholesterol instead of treating fractures and clogged arteries is hopefully an improvement, so a new generation of patients goes to the doctor, not to get well but rather to not get sick...
...plant oil. According to the National Academy of Sciences, “trans fatty acids are not essential and provide no known benefit to human health.” In fact, trans fats decrease levels of HDL ‘good’ cholesterol and increase levels of LDL ‘bad’ cholesterol in the body. This directly increases a person’s risk of heart disease and stroke...
Good clinical studies on pomegranates are few and have used small numbers of subjects. Still, researchers have found such cardiovascular benefits as: decreased blood pressure and oxidation of LDL (bad) cholesterol and improved blood flow through coronary arteries. A study from 2006 reported benefits in men with prostate cancer: 8 oz. daily of the juice slowed activity of residual tumor cells, as measured by serum PSA (prostate-specific antigen) levels. Such encouraging results should inspire larger, better studies...