Word: leaded
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Dates: during 1990-1999
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Less than a minute later, the Crimson struck again as Totman nailed her first collegiate goal off of a Yenne pass to give Harvard a commanding three-goal lead with under 20 minutes to play...
...Princeton, M.I.T. and Washington University, who cleverly altered its DNA--or, more precisely, that of its genetic forebears--in ways that changed the reactions between neurons deep within its tiny cranium. The result, say its creators, is a strain of mouse (which they nicknamed "Doogie," after the precocious lead character of the old TV show Doogie Howser, M.D.) that is smarter than his dim-witted cousins. Not only that, the scientists wrote in last week's issue of the journal Nature, "our results suggest that the genetic enhancement of mental and cognitive attributes such as intelligence and memory in mammals...
...order Rodentia, as some headline writers have portrayed him, most psychologists and neurobiologists are convinced that its memory and learning ability have indeed been enhanced. That has important implications. It suggests that even though the gulf between mice and men is continent-wide, this sort of research may eventually lead to practical medical results for humans, such as therapies to treat learning and memory disorders, including Alzheimer's disease, a condition likely to afflict more and more people in an increasingly aging population. In fact, the Princeton scientists are talking to drug companies about commercializing their work...
...altered mice grow up looking and acting just like ordinary mice, with no evidence of seizures or convulsions, according to Tsien. That's critical. The NMDA receptor shows up throughout the brain, and though calcium is crucial to learning and memory, too much of it can lead to cell death. That's what happens during a stroke: when brain cells are deprived of oxygen, they release huge amounts of glutamate, which overstimulates nearby NMDA receptors and kills their host cells. Nature may have designed NR2B-based receptors to taper off in adult brains for a reason. Some scientists fear that...
Doctors and medical associations are disturbed by the antivaccine sentiment in some communities. They fear that it could erode public confidence in the nation's largely successful vaccination policies and lead to outbreaks of many infectious diseases now held in check by inoculations...