Word: leape
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...leap from a mouse study to a human study, of course - and an even bigger leap to consider developing a G9a-based treatment for addiction. The protein regulates so many genes that such a drug would almost certainly have unwanted and potentially deadly side effects. But a better understanding of the G9a pathways could lead to the development of safer, more specific drugs. And studying the genes that control G9a itself could also help screen people at risk for cocaine addiction: those with naturally lower levels of the protein would be the ones to watch. Still, there...
...here, but the overall effect of the heavily padded Committed is like that of being called, over and over, by a friend who wants to talk your ear off about her impending nuptials. Only instead of debating the floral arrangements, she's wondering, Should I really be taking the leap? Halfway through Committed, I wanted to put the phone down and walk away, leaving Gilbert to figure...
Looking back at the awards season of 1998-99, it's hard not to feel some chagrin. That was the year Roberto Benigni did his clown's leap to the stage to pick up his Best Actor Oscar, but in retrospect, the issue isn't that Benigni beat out Nick Nolte, Edward Norton, Ian McKellen and Tom Hanks for the award; it's that Jeff Bridges wasn't even nominated. His deft, hilarious, thrillingly perfect performance as Jeffrey Lebowski, a.k.a. the Dude, in the Coen brothers' genius film The Big Lebowski should have been showered with prizes. Instead, the only...
...raise a dead person," adding good-naturedly, "It did improve my altar call that night." Roberts provided no details. Later his son Richard expanded the revivification claim, asserting that in 50 or 60 cases, Oral and other ministers had raised the dead. It was, perhaps, not that great a leap from one of the original miracles that helped make Roberts' name in the 1950s: he claimed to have prayed with a crippled 10-year-old boy in Roanoke, Va., and, as the story goes, the boy's withered leg - 21 inches short - grew back to normal overnight...
...Michael was excellent tonight,” Donato said. “He was a going concern every time he had the puck, and he’s a guy who’s taken a big leap this year. I think he’ll be a real key player to us as we hopefully surge to a better second half...