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...were flooded with calcium. Doctors wishing to treat these patients hypothesized that blocking the receptor that enables calcium to enter cells could protect stroke patients from severe brain damage. But in the course of researching this possibility, they found that switching off the receptor in a healthy brain cell led to the death of that cell - an unexpected and troubling result, given that many common anesthetics block the same receptor. At first this made little sense, but other researchers began to speculate that preventing calcium entry might be the cause of injury...

Author: /time Magazine | Title: Anesthesia: Could Early Use Affect the Brain Later? | 11/3/2009 | See Source »

...been shown to cause cognitive impairment in rats.) He saw a vicious cycle of apoptosis and the accumulation of beta-amyloid protein - the sticky plaques that build up in Alzheimer's patients' brains - among the cells. But in this case, it may have been an excess of calcium that led to cell death. Xie and his colleagues have since found that the Alzheimer's drug memantine, which works by reducing calcium levels inside cells, can slow the rate of isoflurane-induced cell death. "That certainly suggests that Dr. Turner and we could be looking at the different sides...

Author: /time Magazine | Title: Anesthesia: Could Early Use Affect the Brain Later? | 11/3/2009 | See Source »

...this week in the Journal of the American Medical Association, offers a snapshot of 1,088 H1N1 cases in California that were severe enough to require hospitalization - or resulted in death - between April 23 and Aug. 11 of this year. Experts at the California Department of Public Health, who led the study, say their findings are largely in line with the growing body of data on the worldwide pandemic flu, confirming, for instance, that the 2009 H1N1 flu disproportionately affects younger patients. The California research team found that the median age of hospitalized H1N1 patients was 27, much lower than...

Author: /time Magazine | Title: H1N1: Hitting the Young, Riskier for the Old | 11/3/2009 | See Source »

...bring anything to the floor unless I think I have the votes," he said on Oct. 21. Yet Reid isn't sure he has the votes to bring this bill to the floor, and it's looking unlikely that he'll have enough support to overcome a Republican-led filibuster. Snowe has said the inclusion of Schumer's provision makes it "difficult" for her to vote yes. Senator Joe Lieberman, a Connecticut independent who caucuses with the Democrats, has said he cannot vote for the bill as it stands, and moderate Democrats such as Indiana's Evan Bayh, Nebraska...

Author: /time Magazine | Title: Can Chuck Schumer Push a Public Option Through? | 11/2/2009 | See Source »

Responding to previous international criticism, the Sri Lankan government declared that it would not subject any of its military commanders or civilian officials who led the war to any kind of international investigation or war-crimes tribunal. The apparent request from American officials led to a similar dismissal. In the U.S., the DHS's office of Immigration and Custom Enforcement (ICE), which reportedly made the Fonseka request, refused to confirm or deny the allegation. ICE spokesman Brandon Alvarez-Montgomery said: "If there was an investigation, there's nothing we can provide. Especially in cases that are very sensitive under human...

Author: /time Magazine | Title: The U.S. Wants to Talk to Sri Lanka's Tiger Tamer | 11/2/2009 | See Source »

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