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...Pain study, which was led by Italian neuroscientist Martina Amanzio, reviewed 73 clinical trials conducted between 1988 and 2007. All the previously published trials pitted potential antimigraine medications against sugar pills. The medications included nonsteroidal anti-inflammatory drugs (NSAIDs) such as aspirin and ibuprofen (Advil); triptans, which include Imitrex; and anticonvulsant drugs like Topamax. Those three categories of drugs carry different adverse effects: NSAIDs, for instance, often cause stomach problems; anticonvulsants can cause paresthesia (tingling) and memory impairment. Interestingly, patients who took sugar pills tended to report nocebo problems consistent with whatever drug they thought they might have swallowed...

Author: /time Magazine | Title: The Flip Side of Placebos: The Nocebo Effect | 10/13/2009 | See Source »

...fascinating article in Wired magazine noted earlier this year that the positive placebo response to drugs has increased during clinical trials over the past few years. The article speculated that drug advertising - which exploded after 1997, when the Food and Drug Administration began allowing direct-to-consumer ads - has led us to expect more from drugs. Those expectations, in turn, have made us feel better just for popping a pill. (Placebo responses can also occur simply when you book appointments with doctors or psychotherapists.) (See the most common hospital mishaps...

Author: /time Magazine | Title: The Flip Side of Placebos: The Nocebo Effect | 10/13/2009 | See Source »

...this country has moved on gay issues: Ting has such a strong sense of entitlement that a routine historical occurrence in democracies - the snatching back of rights that have been reluctantly given to despised minorities - came as a surprise to him. It is that sense of entitlement that led to today's march, which Ting and so many of his cohort put together...

Author: /time Magazine | Title: The Gay March: A New Generation of Protesters | 10/12/2009 | See Source »

...risk to their professional integrity. Murdoch himself has been accused of dropping BBC News from Star TV satellite packages and axing a critical book by Chris Patten, the last British governor of Hong Kong. At a time when media are still reeling from the economic downturn and the Internet-led destruction of traditional advertising and subscription models, China has money to spend and offers new markets for foreign media. The risks are high. Not only could Western media players miss out on a big deal in China, they could sell their soul...

Author: /time Magazine | Title: How Much Will Global News Outlets Bet on China? | 10/12/2009 | See Source »

...Agliotti is a familiar name in South Africa. He is charged with the murder of his former mining boss and friend Brett Kebble, who was a major donor to the ANC's Youth League, an organization that both Selebi and Nelson Mandela once led. Agliotti denies killing Kebble, who was shot dead as he drove near his house in Johannesburg in 2006, but has admitted taking part in what he described as an "assisted suicide." Agliotti has said that Kebble, who had severe money troubles, had wanted to die and that he had merely helped with arrangements. The case goes...

Author: /time Magazine | Title: Corruption Trial Marks Major Test for South Africa | 10/12/2009 | See Source »

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