Word: lederer
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Dates: during 2000-2009
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...understand better the genetic basis of cancer, Philip Leder, a molecular geneticist at the Harvard Medical School and his colleague Timothy Stewart, have bred a line of transgenic mice that may someday serve as a model for human breast malignancy. He designed a DNA hybrid consisting of a gene called c-myc, which has been implicated in animal and human cancer, linked to a regulatory segment of another gene that is expressed in developing and lactating breast tissue. Soon after female mice with the injected gene give birth and begin nursing, they grow sizable tumors in their breasts. Perhaps more...
While the 1992 European patent had fully protected the method of genetic manipulation used by John Emory Andrus Professor of Genetics Philip Leder ’56, then-Harvard researcher Timothy Stewart and DuPont, the ruling marks an additional step back from a 2001 decision that restricted it to rodents...
Despite the limitations, Leder welcomed the ruling...
...United States Patent and Trademark Office granted a patent to Leder and Stewart, making “OncoMouse” the first “transgenic non-human mammal” to be patented...
...Leder also noted that the decision could pave the way for advances in the field...