Word: lederer
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...thought that the problem was that the fundamental control of that gene had been broken, or left behind, so that when it was brought into the new chromosome, it was brought in under the influence of a different control region," says Leder...
...Leder says the female would give birth to a litter of mice, some of whom will have taken up that gene...
Sure enough, after 300 days, Leder says, 50 percent of the mice had developed breast cancer...
Another important result, according to Leder, was that the tumor was only present in a certain part of the animal's breast...
This led to the conclusion that the gene suspected as causal in Burkitt's lymphoma was necessary but not sufficient for cancer, Leder says. It was also concluded that the gene could cause cancer in other mammals, and in regions of the body other than the blood...