Word: leukemias
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Dates: during 1990-1999
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...Princeton. But Hogue must have realized that he would have to serve at least one year of his five-year larceny sentence back in Utah. He applied for a one-year deferment, claiming this time that he needed to care for his mother, whom he said was dying of leukemia in Switzerland. Evidently, Hogue's fictitious mother had risen from her Bolivian grave only to travel to Europe and contract cancer...
Anissa Ayala, the leukemia-stricken girl whose parents conceived another child in the hope of providing her with a blood-marrow donor, was a hot subject too. What was the news? Among other things, her family's reaction to the NBC movie For the Love of My Child: The Anissa Ayala Story. "I really enjoyed it," Anissa's mother told reporter Kelly Lange. "I cried through the whole movie...
Anderson, then at the NIH, with colleagues Dr. R. Michael Blaese and Dr. Kenneth Culver, extracted T cells from the little girl's blood and exposed them to a mouse-leukemia retrovirus that had been rendered harmless and endowed with a normal ADA gene. Invading the T cell, the retrovirus acted as a vector, depositing its genetic material, including the ADA gene, in the cell nucleus. After the re-engineered T cells were cultured, a process that produced billions of them, they were infused back into the child's bloodstream, where their new gene began producing the ADA enzyme...
...term," he says, "I think that gene therapy will be applied to a broader and broader range of diseases, with more and more clever approaches." He points to one brain-cancer trial that received initial approval just last week. Researchers will splice a herpes simplex gene into a mouse-leukemia virus that has been rendered harmless by genetic engineering, and insert the altered virus directly into the brain tumor. The virus, as is its nature, will promptly invade the nucleus of the tumor cells, endowing them with the herpes gene and making them susceptible to ganciclovir, an anti-herpes drug...
...police radars. Dozens of highway patrolmen have come forward to complain of tumors of the eye, the cheek or the testicles (from jamming radar guns between their legs). And there is a growing body of evidence showing that living near power lines can quadruple the risk of contracting childhood leukemia...