Word: leukemias
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Among victims of the half-dozen or more familiar forms of leukemia, he says, it is common for an AIHA process to develop at some stage of the disease. In the AIHA phase, though red cells are the likeliest victims of autoimmune destructive processes, it is not unusual for the platelets (the tiniest solids in the blood, essential for clotting) to be destroyed...
...From this," Dr. Dameshek told the New York Academy of Sciences, "it is only a step to the thought that autoimmune reactions and certain types of leukemia might occur simultaneously, and in fact be one and the same thing." What makes this possibility especially intriguing is the fact that no "cause" of leukemia is known, though there is increasing evidence that it may be triggered by a virus...
...Dameshek has built a research bridge from the leukemias, or "blood cancers," to infectious mononucleosis, which he calls a "fascinating disease." It is, he says, at one and the same time an infection (presumably caused by a virus), a complex immune reaction, and an atypical, self-limiting form of leukemia. In "mono," several abnormal types of antibody are found at the times when the patient's lymph glands are overactive. Where the "not-self" or foreign proteins come from to start this process is not certain, but the likeliest source is the original virus, acting on lymph cells...
...onetime champion marksman, fencing, judo and chess expert (he once played six simultaneous games blindfolded in an exhibition), who predicted the 1929 crash six weeks in advance as well as the turnabout in July 1932, ran the business from a 40-room turreted castle in suburban Tarrytown, N.Y.; of leukemia; in Manhattan...
Last spring, when some of the same doctors had a male patient of 26 dying of leukemia, they decided to give him marrow transplants. But whose marrow? His parents were still living; so were three brothers and a sister. Rather than trust their own judgment in picking which relative had the closest-matching marrow cells, the doctors left the choice to nature...