Word: leveen
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Writing in JAMA, the Journal of the American Medical Association, Dr. Harry H. LeVeen and his colleagues explained that their experiments depended on a significant difference between ordinary tissue and tumors. Because most tumors lack a fully developed network of blood vessels, blood flows much more sluggishly through them than through normal tissue, and heat is not so quickly transported out. Thus tumors are far more susceptible to heat. At high enough temperatures, the malignant cells are killed...
...experiments, LeVeen, a surgeon who also teaches at Brooklyn's Downstate Medical Center, employed radio-frequency generators that operated at 13.56 megahertz, in the frequency range used by short-wave broadcasters. The signals were sent into the body by electrodes or other devices attached directly to the skin immediately above the tumors. The doses, lasting up to 30 minutes, never exceeded 25 watts-the power drawn by a small light bulb-per square inch. The lightly sedated patients generally felt no pain and did not suffer serious damage to skin or other tissue. Nonetheless, the radiation was strong enough...
...LeVeen and his colleagues are understandably excited by their technique. In conjunction with other treatments like immunotherapy (TIME cover, March 19, 1973), it could provide a promising new weapon against substantial-sized tumors; it would not be effective against leukemia and other cancers involving widely dispersed malignancies. LeVeen also agrees with the authors of an accompanying editorial in JAMA, Drs. Joan M. Bull and Paul B. Chretien of the National Cancer Institute, who urge additional tests on patients-with special attention directed toward any adverse side effects-before wide-scale application of heat therapy in cancer treatment. Such trials...
Last week surgeons at New York's Downstate Medical Center in Brooklyn described an antiseptic suture that seems to be just what Lister was looking for. Dr. Harry H. LeVeen and colleagues reasoned that if old-fashioned silk suture thread offers hiding places for germs, it will also have room to absorb a fair amount of antibacterial chemical. After swelling the silk to make it still more absorbent, they soaked it in a preparation of benzethonium, a modern, potent germ killer. Then they tested the sutures in mice, and got 100% protection against infection for at least five days...