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CHICKEN WITH PLUMSMARJANE SATRAPIThe author of the Persepolis books continues to plumb her family history in Iran for fascinating stories. This one focuses on her great-uncle, a celebrated musician who, family lore says, decided to lie down and die after his wife broke his instrument, a tar, over her knee. Satrapi chronicles the eight remaining days of his life as he converses with his wife, his children, his friends and eventually the angel of death. Satrapi's simple black-and-white drawing style, combined with the fantastical elements of her narrative, turns Chicken with Plums into a great bedtime...
Those molecular switches lie in the noncoding regions of the genome--once known dismissively as junk DNA but lately rechristened the dark matter of the genome. Much of the genome's dark matter is, in fact, junk--the residue of evolutionary events long forgotten and no longer relevant. But a subset of the dark matter known as functional noncoding DNA, comprising some 3% to 4% of the genome and mostly embedded within and around the genes, is crucial. "Coding regions are much easier for us to study," says Carroll, whose new book, The Making of the Fittest...
...weeks of gestation. Although the gene's precise function is unknown, that happens to be the period when a protein called reelin helps the human cerebral cortex develop its characteristic six-layer structure. What makes the team's research especially intriguing is that all but two of the HARs lie in those enigmatic functional noncoding regions of the genome, supporting the idea that much of the difference between species happens there...
...Walnut Creek, Calif. "They had fire, burial ceremonies, the rudiments of what we would call art. They were advanced--but nothing like what humans have done in the last 10,000 to 15,000 years." We eventually outcompeted them, and the key to how we did so may well lie in our genes. So two years ago, Svante Pääbo, the man who deconstructed the FOXP2 language gene and has done considerable research on ancient DNA, launched an effort to re-create the Neanderthal genome. Rubin, meanwhile, is tackling the same task using a different technique...
...easy one. Like any complex organic molecule, DNA degrades over time, and bones that lie in the ground for thousands of years become badly contaminated with the DNA of bacteria and fungi. Anyone who handles the fossils can also leave human DNA behind. After probing the remains of about 60 different Neanderthals out of the 400 or so known, Pääbo and his team found only two with viable material. Moreover, he estimates, only about 6% of the genetic material his team extracts from the bones turns out to be Neanderthal...