Word: life
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Dates: during 1980-1989
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...cocaine engages three separate neurotransmitter systems: those based on dopamine, serotonin and norepinephrine. Taken together, these networks govern the human ability to experience pleasure, from watching a sunrise to having sex. Blocking all these pleasure centers -- as methadone blocks the heroin high -- would literally take the joy out of life, says Yale's Kosten. "We'd turn out automatons." Addicts trying to quit cocaine go through a stage called anhedonia, a sort of spiritless limbo that typically drives the user to take the drug again. At best, researchers can hope for a patchwork of drugs to block discrete stages...
TRUST by George V. Higgins (Henry Holt; $18.95). Another installment of petty schemers and low-life banter for Higgins fans, but other readers will feel it takes far too long for the protagonist, a crooked used-car salesman, to get his comeuppance...
...Moving Image. Triple-threat Walton has an Oscar, two Tonys and an Emmy for his work in film, theater and television. Whether creating a gleaming silver-and- white Deco hotel room for Lend Me a Tenor or a ship caught in The Tempest's hurricane, Walton gives life to a world suggested by words. Through August...
...mass dissatisfaction? A major increase in working hours, coupled with a corresponding rise in stress, has led to an erosion in the quality of life for many lawyers. Law firms often require that each year attorneys do 2,000 to 2,500 hours of work that can be billed to clients, almost a third more than a decade ago. That frequently translates into twelve-hour-plus workdays and busy weekends as well...
Singh says his past and present connect perfectly. He was always good at organizing things. He has always tried to live a moral life. "I don't see any divergence in my program," he says. In 1979 he borrowed $7,500, started rehabbing buildings in New England and prospered; luck or savvy got him into Key West before the Northeast real estate market went flat...