Word: lifespan
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...extends the lifespan of every organism it has been put into,” he said of the gene, adding that these organisms include yeast, worms, and fruit flies. Tests on mice are currently ongoing...
Sinclair said that the role of Sir2 is thought to be related to a well-known phenomenon in rats whereby restricting the animals’ caloric intake can increase their lifespan...
...researchers—who included Dudley Lamming, Oliver Medvedik, and Magda Latorre-Esteves, in addition to Sinclair—reveals that Sir2 does not serve this function alone. Rather, a group of related genes—the Sir2 family—plays a major role in regulating lifespan. Sinclair said that one of the genes in the family appears to control functions such as fat metabolism and cell survival, while another controls body temperature and the efficiency with which an organism uses energy, and yet others protect against diabetes...
According to Sinclair, the Sir2 genes are effective in extending lifespan because they control the body’s own defenses against disease—defenses which, he argued, modern medicine has not utilized to their full potentials...
Scott also points to the socio-economic plight of Native Americans, saying that many people are unaware that Natives have the second shortest lifespan of any ethnic group in North America...