Word: lipids
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...away. Only in the past few years have doctors had the tools to achieve such reductions. LDL-pheresis is one example, while new experimental drugs like Mevinolin, particularly when combined with existing drugs, also hold great promise. "What's exciting now," observes Biochemist Thomas Parker, director of the Rogosin lipid laboratory, "is that for the first time researchers all over the world can begin to study the possibility of reversing atherosclerosis...
...side effects, the long-term consequences are unknown. There is a theoretical risk, doctors say, that antibodies in the filter could leach out into the blood and cause allergic reactions. Many believe the inconvenience and expense of the procedure will limit its applicability. Dr. Antonio Gotto, a leading lipid researcher, estimates that a year of weekly treatments would cost $40,000. Even an LDL-pheresis enthusiast like Chazov agrees that it is not "a means of mass treatment for atherosclerosis." For that, he says, one must turn not to miraculous medical intervention, but to good, old-fashioned prevention, however boring...
...this story, Gribben sought out experts at the University of Cincinnati Lipid Research Clinic, interviewed food-industry spokesmen and talked to Milwaukee doctors studying heart-disease risk factors such as smoking and job-related stress. Crooks interviewed scientists at universities and medical centers, spoke with teachers participating in a health-improvement scheme and talked to National Institutes of Health researchers about the amazing Pima Indians, who have very low heart-attack rates. Since last year, when she covered the progress of Artificial Heart Recipient Barney Clark for TIME, Crooks has become something of an expert on medical subjects, although...
...lesson is plain, says Dr. Charles Glueck, director of the University of Cincinnati Lipid Research Center, one of twelve centers that participated in the project: "For every 1% reduction in total cholesterol level, there is a 2% reduction of heart-disease risk." This, says Project Director Basil Rifkind, is the evidence scientists have been waiting for. "It is a turning point in cholesterol-heart-disease research...
...fact that the "diet-heart hypothesis," as the cholesterol link with coronary disease is known, remains a theory and the subject of heated debate. True, studies have established that high cholesterol levels in the blood are associated with increased heart disease. But, admits Dr. Basil Rifkind, chief of the lipid metabolism branch of the National Heart, Lung and Blood Institute, "what's missing is the proof that you can prevent heart disease by reducing cholesterol...