Word: lipitor
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...volume, but its fragmented industry of 20,000 companies is still stunted in terms of revenues. Last year, the total value of India's drug sales including exports came to $6.5 billion, less than the $8 billion Pfizer raked in from a single blockbuster product, its anticholesterol drug Lipitor...
...three diabetics will die from heart disease or stroke, yet diabetics often go undertreated for these life-threatening complications. A pair of studies offered a strong argument last week against such neglect. Drugs called statins, such as Zocor and Lipitor, which are widely used to lower cholesterol levels, were found to significantly reduce strokes and heart attacks in diabetics. The need is growing: the Centers for Disease Control (CDC) reports that more than 17 million Americans have diabetes, up 50% over the past decade. And it's only going to get worse; 1 in 3 children born...
...furiously investigating all the other things these drugs might be doing for the heart besides lowering cholesterol levels. It turns out that the noncholesterol effects of statins, such as controlling clotting and inflammation, may be as important as the cholesterol effects. In a study of patients given atorvastatin (Lipitor) as soon as they arrived at a hospital complaining of chest pain, it was found that those who took the drug for four weeks after their cardiac event were significantly less likely to be rehospitalized or feel increased chest pains than patients who did not take the statin. However, another study...
...three otherwise healthy cardiologists whether they are taking a cholesterol-lowering drug, and chances are good that at least two of them will reply with a hearty "You bet." Their prescription of choice: one of a group of drugs called statins--marketed under such names as Lipitor, Pravachol and Zocor--that have been proved to reduce deaths among heart-attack survivors by more than 40% over five years. In effect, the doctors are taking a highly educated gamble that the medications, currently taken by more than 10 million Americans, will be just as effective in those who do not necessarily...
...adopting a low-fat diet, getting plenty of exercise and losing a little weight, most people can reduce their total cholesterol levels an average of 10% to 20%. Yet that's only about half the effect of the weakest of the currently available statins. Stronger drugs, like Pfizer's Lipitor, can lop off 50%, and AstraZeneca is testing a "superstatin" that reportedly reduces cholesterol levels as much as 70%. (In each case, statins work best when a low-fat diet is adopted...