Word: liverance
(lookup in dictionary)
(lookup stats)
Dates: all
Sort By: most recent first
(reverse)
...with Rezulin, the diabetes drug that was taken off the market last week. The FDA approved the medication in 1997 after tests on 3,000 people showed that it could help control Type 2 (formerly adult-onset) diabetes, which affects 15 million Americans. Although some test subjects developed abnormal liver reactions, no one suffered permanent damage, and no one died. Now that millions have taken Rezulin, however, it has been linked to at least 90 cases of liver failure, 63 of which resulted in death...
...memorable case, Weinstein predicted that a critically ill patient with both liver and kidney failure would get better within a month, Harrington remembered. To the amazement of Dr. Harrington and other doctors, this diagnosis proved to be correct...
...tough week for the Food and Drug Administration. On Tuesday, the Supreme Court dealt a decisive blow to the agency's authority, ruling the FDA does not have regulatory power over tobacco. And Wednesday, after the diabetes drug Rezulin was linked to 63 deaths and 90 cases of liver failure, the FDA finally convinced pharmaceutical giant Warner-Lambert to pull it from the market. The agency will face inevitable questions: Why would the FDA approve a drug with known toxic side effects? Can consumers trust their safety to the agency's testing standards...
...important to know the history of Rezulin before leveling any charges, says TIME medical writer Christine Gorman. "All prescription drugs have risks and benefits, and Rezulin was no different," she says. "Patients with liver problems had to be watched very carefully while taking this drug, but it helped a lot of people with diabetes." And that cost-benefit ratio played into the FDA's timing; the agency did not pull Rezulin until other, less toxic drugs became available...
...trial ended in January 1997, Monahan's fatigue persisted. A few months later, doubled over with abdominal pain, he went to a doctor. A series of X rays and other scans revealed that Monahan was suffering from advanced colon cancer--so advanced that the disease had spread to his liver. He died Jan. 24, 1998, two weeks after his 42nd birthday...