Word: livered
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Dates: during 1960-1969
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...Brigham even as the patrolman's lifeless body was wheeled into an operating room. There Drs. Nathan Couch and Anthony Monaco made a long vertical incision on the right side of the abdomen. Within three minutes they cut down to the portal vein, which drains into the liver; they then injected a frigid solution to cool the precooled liver down still more. They completed their work in 24 minutes and dropped the liver into a cold saline solution in a sterilized container...
...Hour Limit? This was not the first transplant of a human liver. That was done last March in Denver, where surgeons and physicians from the University of Colorado Medical Center and the nearby VA Hospital have pooled their talents in a transplant team. By now the Denver group has done four transplants, with one patient living 22 days after the operation, when he died of pneumonia. The Boston and Denver teams have traded reports of their progress, and their methods are remarkably similar, though they differ in some details...
Denver's Dr. Thomas E. Starzl and William R. Waddell feel strongly that a liver should be hooked up to its new blood supply within two hours of being disconnected from its original host. They have not yet been able to make the transplant as fast as that, and neither did Dr. Moore. But the Callahan-Bingel transplant had an advantage in that the liver had been precooled for 40 hours, which gave its tissues time to adjust to a lower metabolic rate...
Since man can live only about 36 hours without liver function, and three of the Denver patients lived longer than that, it is clear that the transplanted organs have worked. So did Joseph Bin-gel's, for eleven days. Then he died...
...attempt to save Bingel, helped by a widow's understanding, had been a noteworthy feat of medical and surgical cooperation. It failed, said Dr. Moore, "because all transplant patients face the problem of the organ's getting used to its new host-the host and the liver have to learn to live together." Renewed attempts to teach them to live together were certain to be made soon. Even as Joseph Bingel died, a gathering of transplant experts convened in Washington to figure out improved methods of increasing those chances...