Word: livered
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Dates: during 1980-1989
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...fear, the copycats have not yet killed anyone. But whoever put mercuric chloride into Excedrin Extra-Strength capsules purchased by William Sinkovic of Aurora, Colo., narrowly missed. Sinkovic, 34, suffered acute kidney and liver failure. Emergency surgery saved his life, but he is still in serious condition...
...characterized by tics and involuntary outbursts of swearing (100,000 Americans); Prader-Willi syndrome, a children's ailment that causes huge weight gains and often kills its victims before they are 20 (2,000); Wilson's disease, a condition marked by abnormal accumulation of copper in the liver and brain (1,000); Huntington's chorea, the degenerative disease of the mind and nervous system that caused the death of Folk Singer Woody Guthrie (14,000); as well as various rare cancers...
...cells, which reduce antibody output. Healthy individuals have twice as many helpers as suppressors. In AIDS victims, the ratio is reversed; helper cells are depleted. No one knows what happens to these cells, but New York Immunologist Roger Enlow has a theory: "Just as hepatitis B virus preferentially attacks liver cells, it is probable and even likely to have a virus that at tacks helper T cells...
...experimental use in the U.S. since 1979, cyclosporine, says Sandoz, has dramatically increased survival rates for kidney transplants, from a range of 45% to 55% to a range of 80% to 90%, and for liver transplants from 30% to 70%. The first heart transplant using cyclosporine was performed in December 1980 by a Stanford University team, including Oyer and headed by Dr. Norman Shumway, who had pioneered the first heart transplant in the U.S. twelve years earlier. The team has now done 36 transplants using cyclosporine, and although Oyer cautions, "It's too early to tell," the preliminary...
...long afterward, Lilly sent out a letter to U.S. physicians emphasizing that elderly people with impaired kidney or liver functions should not be given the full recommended dosage of the drug. Last week a Lilly research vice president denied knowing about the British fatalities from liver disease until informed by the FDA in May. For his part, FDA Commissioner Hayes testified that his agency did not learn of them earlier because "we don't have the wherewithal to solicit information from all countries where a drug is used...