Word: livered
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Dates: during 2000-2009
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...Coumadin is the "blood thinner" we use when you've had a stroke, heart valve replacement or blood clot. It works by poisoning an enzyme in your liver that helps produce clotting factors. Its blood thinning (anticoagulating) effect comes on slowly but can quickly become (dangerously) greater than we want when you take different drugs or even different foods. The anticoagulation we want can easily overshoot - with dire consequences. It also can render ineffective or too effective, other drugs that are processed in the liver. Getting you on just the right dose of coumadin takes about a week, then...
...placentas, and even in fully formed adult organs. While not as flexible as embryonic cells, cord and placental cells have proved more valuable than scientists initially hoped. Although about 90% of cord-blood stem cells are precursors for blood and immune cells, the remaining 10% give rise to liver, heart-muscle and brain cells and more. Over the past five years, cord-blood transplants have become an increasingly popular alternative to bone-marrow transplants for blood disorders, particularly when a bone-marrow match can't be found...
...Duke University Medical Center. Children with blood diseases that were almost certainly fatal a decade ago have got cord-blood transplants that essentially cure them. Now she and her team are taking a more targeted approach by attempting to differentiate cord-blood cells to address heart, brain and liver defects. "I think cord-blood cells have a lot of promise for tissue repair and regeneration," says Kurtzberg. "But I think it will take 10 to 20 years...
...they are useful Although they are primarily made up of blood stem cells, they also contain stem cells that can turn into bone, cartilage, heart muscle and brain and liver tissue. Like adult stem cells, they are harvested without the need for embryos...
Researchers have discovered that many tissues and organs contain precursor cells that act in many ways like stem cells. The skin, intestines, liver, brain and bone marrow contain these stem cell-- mimicking cells, which could become a reservoir of replacement cells for treating diseases such as leukemias, stroke and some cancers. "Brain stem-cells can make almost all cell types in the brain, and that may be all we need if we want to treat Parkinson's disease or ALS," says Dr. Arnold Kriegstein, who directs the University of California at San Francisco's Institute for Regeneration Medicine. "Embryonic stem...