Word: livers
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Dates: during 1960-1969
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...Hoagland's hunch seemed to pay off. Methylphenidate not only roused would-be suicides from their comas, but it was also effective for patients suffering from coma resulting from brain damage and liver failure. For the first time, such patients were able to swallow food and medication, cough up sputum and mucus, thus avoiding one of coma's worst complications, suffocation...
...recent years, doctors began to agree that this kind of adult diabetes did not result from any failure of the pancreas to produce insulin. They speculated that insulin, although produced in the right amount, was destroyed somewhere in the body, perhaps in the liver. Now they know better. Latest findings about diabetes, confirmed independently by Stanford University's Dr. Gerald Reaven and the University of Michigan's Dr. Lawrence Power, show that the level of insulin, or at least of what they cautiously call "insulin-like activity," is actually higher in the blood of obese adult diabetics than...
Help in Crises. None of the eight patients lived, and none were expected to. Seven were victims of severe al coholic cirrhosis, and the pig-liver substitute worked well for only about six hours at a time, which was nowhere near long enough to let the patients' livers recover. But only two men failed to respond to the treatment, and five came out of their coma long enough to obey spoken commands. One asked for a cigarette on the operating table, and another was coherent for four days...
...liver was washed free of its own blood, cooled down to 54° F., and injected with antibiotics to kill any bacteria that might be present. Tubes were inserted in one of the patient's main arteries and one of his large veins; his own heart served as the pump to send his blood into the pig's liver. From there, the blood went back into the patient's vein after being rewarmed along the way to a normal...
...Kentucky surgeons' patients had two perfusions; one who had three responded well to the first and second. Dr. Eiseman now believes that if pig-liver perfusions can be prolonged to 24 hours, they may be of real help in crises for hepatitis patients and cirrhosis victims who still have a little liver function remaining, and also for transplant recipients immediately after surgery if liver transplants ever become practicable...