Word: livers
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Dates: during 1960-1969
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...quietly did he die of a liver ailment at the age of 24 in Manhattan on Oct. 4 that not a line made the news columns. But when the will of Robert Vanderpoel Clark Jr. was probated last week, it showed an estate of $26,554,200, held principally in trusts and be queathed equally to his mother and wife of 2½ years. Clark was a great-grand son of Singer Manufacturing Founder Alfred Corning Clark, and he inherited the bulk of his fortune when his great-uncle died last February...
...Early in his research Dr. Bloch learned that most of the cholesterol in the bodies of both animals and men comes not from cholesterol in food (though butterfat, egg yolks and meat fats contain much of it) but from built-in cholesterol factories. These factories are mainly in the liver, but many of the body's other cells can make some cholesterol. To discover how they do it, Dr. Bloch had to go back to the biochemical beginning...
...huge and diverse class of chemicals-including many fatty substances and most adrenal and sex hormones-having one thing in common: a four-ring cluster of carbon atoms, known as "the steroid nucleus." Other attached atoms give each steroid its distinctive character (see diagram). By growing rat-liver cells in the test tube, Dr. Bloch learned that they make cholesterol from the much simpler acetate ion (acetic acid minus a hydrogen ion). "My work since then," he says, "has been on the processes that the cell uses to manufacture the cholesterol molecule. This is a fantastically complex sequence of approximately...
...shall not bother you with symptoms, except to say that I am now having recurrent liver trouble, plus pretty nearly all the other afflictions normal for a 53-year-old man in a tired, rundown condition. My doctor says, in effect, that I am like the One Hoss Shay just prior to its famous last journey-still able to take the road, but unless immediately repaired, quite likely to come apart for good...
...circulatory diseases, including strokes, which accounted for 55% of the nearly 2,000,000 deaths in 1962. The second-place killer is cancer (16%). The other major causes of death: accidents (6%), diseases in the newborn (4%), influenza and pneumonia (3%), diabetes (2%), congenital malformations (1%), cirrhosis of the liver (1%) and suicide...