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Wilson expects Phase I trials using AAV to begin later this year, first for the treatment of hemophilia and later for a form of muscular dystrophy, a liver metabolic disease and retinitis pigmentosa, an eye disorder. "It's kind of a new wave," he says...
...knows why the Kinki team managed to bat .800 (while Dolly's creators needed 29 embryos to get one hit). Japanese scientists hope to learn more when other calves--cloned from liver, kidney and heart cells--are born next spring. The beef industry is anxiously awaiting the answer: the clones come from a line of prize cows whose meat sells for $100 a pound...
Most of us absorb only 10% to 15% of the iron in our food. But people with hemochromatosis soak up 75% or more. The body stores the excess wherever it can--in the liver, heart, pancreas, joints--where it eventually causes permanent tissue damage. But the changes can be subtle. For example, iron buildup in the pituitary gland, which controls hormone production in the brain, may trigger impotence in men and early menopause in women. People of Scottish, Irish and Welsh backgrounds appear to be affected more than others--possibly because their ancestors ate a diet deficient in iron. There...
DIED. FLIP WILSON, 64, caricaturist; of liver cancer; in Malibu, Calif. Creator of such pop cultural icons as Geraldine--the proud, sassy black woman who warned admirers that "What you see is what you get!"--Wilson was the first African-American entertainer to host a variety show. His goofy, outlandish style of humor was defiantly nonpolitical. "Funny is not a color," he said. "My main point is to be funny. If I can slip a message in there, fine...
...doctors have discovered that a cocktail of drugs may be more effective than a single medication against hepatitis C. Until now interferon--injected three times a week--was the only treatment. But studies show that adding the antiviral pill ribavirin can more than double the odds of eradicating the liver disease. And for those who suffer a relapse, the combo increases the chances for a successful treatment fivefold...