Word: livers
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Most science and math Cores at Harvard are like a hazing ritual: you have to get through them, but at the end, all you’re left with is relief, and perhaps a strange pain in your liver. You don’t learn to think critically by memorizing these equations; if anything, you learn to cut corners...
Rimonabant, the weight-loss compound they developed, is the first drug that manipulates the endocannabinoid system, a network of cells in the brain, the liver and fat tissue that regulates hunger by linking appetite to the body's reward and satisfaction system. Rimonabant reduces food cravings by deactivating the cannabinoid receptors. The drug, to be marketed as Acomplia, is being reviewed by the FDA and will be targeted at those who not only carry excess weight but also harbor unhealthy signs of metabolic disorders such as diabetes and hypertension. In half a dozen clinical trials, the compound helped...
...deposits within blood-vessel walls but also cause those plaques to shrink in size. So doctors are asking patients to make simple lifestyle changes, including getting more exercise and eating omega-3 fatty acids, found in certain deepwater fish such as salmon and tuna, because these activities stimulate the liver to churn out more HDL. They also have an added incentive to prescribe the powerful statin drugs that lower LDL because those appear to do double duty, pumping up HDL levels 10% to 15%. And if that isn't enough, they are eyeing the arrival of HDL-boosting pills: Pfizer...
...prevent the headache pain. These drugs can cause some gastrointestinal discomfort, especially for those with sensitive stomachs. Harvey wants to stress that you must never take Tylenol or other acetaminophen while or after drinking, as it can react dangerously with the chemicals in your body and cause permanent liver damage. In the meantime, “hang” in there and get some rest! Best of luck, Harvey “Help Me Harvey” is a health column that will be published biweekly in The Harvard Crimson. Send your questions to harvey@thecrimson.com. All submissions are confidential...
...drug users mature, geriatric biology and life circumstances tend to tighten the drugs' hold. Reduced body mass, slower metabolism and less efficient kidneys and liver mean that the same quantity of drug hits harder and stays in the body longer. Older users who think they're keeping their doses fixed are thus, in effect, steadily increasing them. What's more, the loss of a spouse or job or merely the boredom of retirement could tip the nonuser into experimentation and the borderline user into full-blown addiction. Moses, 57, never touched heroin until 2001, when his wife died. But when...