Word: livers
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...reduces the risk of developing diabetes 30%. And a study of heart-attack survivors finds that Pravachol reduces the odds of stroke 20%. No, it's not time to add statins to the drinking water. They need to be taken every day for life, and they carry risks--including liver damage...
...Using a technology known as electron-beam computed tomography, radiologists take detailed internal pictures from the shoulders to the pelvis. The whole thing takes 10 minutes and provides such information as how much unwanted calcium has collected in your coronary arteries, whether there is an abnormal growth in your liver or colon or whether your bones are showing early signs of osteoporosis. Cost: $500 to $725, little of which your insurer is likely to reimburse...
...envisioned. Last year the company reported results of a clinical trial in which Onyx-015 injections, in combination with chemotherapy, melted away tumors in 8 out of 30 patients with recurrent, late-stage head and neck cancer. In another study, involving 27 patients whose cancer had metastasized to the liver (a condition that usually kills in 6 months), 11 were still alive nearly two years after being treated with high doses of Onyx...
...aimed at halting that process, including some old-line drugs that have turned out to have antiangiogenic properties. Thalidomide, which caused devastating birth defects in some 12,000 children worldwide before it was withdrawn in the early 1960s, is finding a new lease on life against multiple myeloma and liver cancers. Pharmaceutical giant Bristol-Myers Squibb is testing an antiangiogenic drug that was initially developed to keep cancer from worming its way into surrounding tissue. It's also investigating whether low, steady doses of traditional chemotherapy may be able to beat back blood vessels, a treatment that would have...
...work for everyone. So drug companies are studying the biochemical pathways by which the body pulls cholesterol that has already been manufactured out of a cell. "By turning this reverse cholesterol transport on, you'd be able to stimulate removal of cholesterol from vessel walls back to the liver for excretion," says Dr. Richard Gregg, vice president of metabolic- and cardiovascular-drug discovery at Bristol-Myers Squibb. Taken in combination with statins, such drugs could virtually sweep the arteries clean of cholesterol...