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...more per cycle, and the study group at the Massachusetts clinic likely included many patients less deterred by financial issues than women in the general population, possibly distorting the data. Malizia, who now serves as a reproductive endocrinologist at Alabama Fertility Specialists in Birmingham, Ala., suggests, however, that the live-birth rates of her study group skewed lower than they might have, had the study been conducted elsewhere. "In states where there's no insurance coverage, there's lower access to IVF treatment," she says. "Those who pursue it may have a better chance of pregnancy, so our suspicion would...
...analysis of the overall live-birth rate for 6,164 patients at a Massachusetts fertility clinic, researchers from Boston IVF and Beth Israel Deaconness Medical Center found that in women ages 39 and younger who were treated with up to six cycles of IVF, the rate of live births ranged from 65% to 86%; in women ages 40 and older, the live-birth rate...
...study, published in the Jan. 15 issue of the New England Journal of Medicine, and a former clinical fellow in obstetrics, gynecology and reproductive biology at Harvard Medical School. "When we got these results we were quite pleased...[IVF] does restore in the infertile population the same live birth rates that they have in their own age group."(See TIME's Top 10 Medical Breakthroughs...
...study's more than 6,000 participants became pregnant and gave birth, or underwent the full six cycles of IVF before leaving the clinic, which accounts for the range of live-birth rates. Researchers had to extrapolate from their existing data the likely outcomes for patients who discontinued treatment: In the "optimistic" analysis, researchers assumed that the women who discontinued treatment would have had the same success rates as those who continued treatment; the "conservative" analysis assumes a zero success rate among all women who discontinued IVF at that particular clinic. Realistically, say the authors, the actual live-birth rates...
Malizia's study may not break new medical ground, but it presents a new perspective on IVF, in that most studies that analyze the treatment's success rates look solely at the outcomes of individual implantations, not the overall possibility of a live birth. "As far as the patients are concerned, they would like to know not just pregnancy but live birth [outcomes], and not just during that one cycle but over the course of the entire treatment," Malizia says. "The statistics that are out there don't exactly answer the question...