Word: lode
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Dates: during 2000-2009
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Mack attracts attention because both his new and old firms were doing much of the underwriting. At CSFB, star tech banker Frank Quattrone brought in the mother lode: CSFB took public 142 tech companies in 1998-2000. In the same period, while Mack was the top hands-on manager at Morgan Stanley, his firm underwrote 68 tech-stock ipos, according to Thomson Financial. The firms ranked 1 and 3, with Goldman Sachs notched in between...
...turns out the Jones Institute for Reproductive Medicine in Norfolk, Va., has been doing exactly that: taking volunteers' sperm and eggs to create a human embryo for the sole purpose of dismembering it for its mother lode of stem cells...
...self-resuscitators are also being helped by the increasing popularity of vintage clothes. The everything-old-is-new-again trend means wearing Pauline Trigere is cooler than wearing Donna Karan. Old Chanel is better than new. In which case, Texas Pacific Group may have hit the mother lode in the somnolent 150-year-old Bally, which it bought late in 1999. Bally has a reputation for expensive, well-made shoes that register zero on the Richter scale. But the new creative director, Scott Fellows, has something most designers don't: a Harvard M.B.A. (He also attended the Fashion Institute...
...self-resuscitators are also being helped by the increasing popularity of vintage clothes. The everything-old-is-new-again trend means wearing Pauline Trigere is cooler than wearing Donna Karan. Old Chanel is better than new. In which case, Texas Pacific Group may have hit the mother lode in the somnolent 150-year-old Bally, which it bought late in 1999. Bally has a reputation for expensive, well-made shoes that register zero on the Richter scale. But the new creative director, Scott Fellows, has something most designers don't: a Harvard M.B.A. (He also attended the Fashion Institute...
Nature is not the only lode that drug developers are mining. Linezolid, the novel antibiotic just approved by the FDA, is totally synthetic, and that is a great advantage, believes Pharmacia Corp.'s Dr. Gary Tarpley, who led the team effort that produced the drug. "Because this compound has never been seen by bacteria," he says, "it is extremely unlikely that there is any pre-existing resistance out there." Like tetracycline, linezolid blocks protein synthesis, but it does so much earlier in the cellular cycle. No other antibiotic operates in this fashion, yet another reason to expect resistance to develop...