Word: loss
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That discrepancy is not unheard of: many elderly patients develop the brain lesions, plaques and tangled neurological-tissue fibers that are indicative of dementia and Alzheimer's disease, but not all of them exhibit the memory loss and confusion that typically characterize these disorders. In fact, the number of such patients may be greater than researchers first thought. In a November 2008 study, a team of scientists used a new positron emission tomography (PET) brain-imaging technique developed by Drs. William Klunk and Chester Mathis of the University of Pittsburgh to image the brains of live patients - a leap forward...
Past studies have shown that patients who have so-called asymptomatic Alzheimer's disease - those who have the hallmark brain lesions and plaques of Alzheimer's disease but no memory loss - also have enlarged neurons, compared with patients who suffer cognitive impairment. Dr. Diego Iacono, a neuropathology fellow at Johns Hopkins School of Medicine and the future director of the Brain Bank at Sweden's Karolinska Institute, conducted several such studies in predominantly male populations, but his latest research, the study published in Neurology, demonstrates the same patterns in an entirely female population - of nuns. (See pictures of the sisters...
...oxidative stress that damages proteins and DNA and contributes to disease development. "What we're doing with rapamycin," Strong says, "is we're actually tricking the cells into thinking that they're depleted of nutrients. Rather than the animals losing weight - we haven't noticed any weight loss - they may be just using their proteins more efficiently, and then repairing proteins more efficiently...
...husband's job loss is a family event that affects everyone - especially spouses, according to Alan Pickman, a psychologist and outplacement specialist with Lee Hecht Harrison as well as the author of The Complete Guide to Outplacement Counseling. While both the husband and wife may struggle with new financial fears and feelings of anger and betrayal, "the spouse's response may be even more intense than it was for the individual male who lost his job," says Pickman. Most experts agree that may be because wives feel powerless - both about the job loss as well as the family's future...
...Federal Reserve Bank of Boston, who studied negative equity in Massachusetts during the late 1980s and early 1990s when home prices dropped 23%, argues that most walk-aways are likely driven by the combination of two things: both negative equity and an economic hardship, such as job loss. (See 10 ways your job will change...