Word: lsd
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Dates: during 1960-1969
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...pharmacology of LSD is not yet fully understood. The tracing of injected radioactive LSD shows that only an infinitesimal amount ever reaches the brain-and that is gone before the effects begin to be felt. It is generally thought, therefore, that LSD does not act directly but triggers an unknown series of metabolic processes. These in turn somehow affect the midbrain, seat of the intimate interchange between emotional response, awareness of external and internal stimuli, and the sympathetic and parasympathetic nervous systems. Tranquilizers or barbiturates halt LSD's effects, while stimulants like amphetamine tend to elevate them. LSD...
Last month two Senate committees held hearings on the uses and abuses of LSD. In testimony, the Food and Drug Administration and the National Institute of Mental Health opposed federal legislation that would have made mere possession of LSD a crime-although California and Nevada have since passed such statutes. Restrictive legislation, say Administration officials, would only cut off the supply for legitimate research. (This has already partially happened because of LSD's notoriety.) Besides, it is argued, the situation can be handled by merely sharpening existing rules, to prohibit the unregistered manufacture, traffic and sale of LSD...
...acid, which is difficult to make (it is derived from ergot, a cereal fungus), continues to be smuggled in from Canada, Mexico and Europe. Given the acid to start with, LSD is relatively easy to cook up for anyone with a working knowledge of chemistry. Essentially, what is required is a batch of lysergic acid dissolved in some other chemicals plus a solution of diethylamine (a volatile liquid used in processes like vulcanizing). The two batches, cooled to freezing and stirred together, result in a solution that contains LSD. The trick is to extract the LSD from the solution. This...
...LSD is generally black-marketed in impregnated sugar cubes, costing from $2.50 to $5 for 100 micrograms, enough for an eight-to ten-hour trip. Another way of transporting small quantities is to mix them in water, soak the solution up in a handkerchief and let it dry-to be cut up later into squares, which LSD users chew. LSD is hard to track down because the compound is colorless, tasteless and odorless, and so potent that a gram, equal to one million micrograms, or 10,000 trips, could be stashed in a single cigarette. So far, illegal LSD...
...mild ones are morning-glory seeds, nutmeg and marijuana. The moderately potent ones are the mescaline of Weir Mitchell's experiment, psilocybin (derived from the Mexican Indians' "sacred mushroom"), bufotenine (a constituent of Amanita muscaria), and dimethyltryptamine (found in cohoba). By itself on the third level is LSD. It has 100 times the potency of psilocybin and 7,000 times that of mescaline, which is itself considerably more powerful than marijuana...