Word: lunge
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Dates: during 1950-1959
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...died after fractures of the leg, thigh or pelvis. So Drs. Simon Sevitt and Nrall G. Gallagher took 300 consecutive admissions of patients over 55 with broken thighs, and treated half of them with the anticoagulant phenindione to see whether it would prevent blood clotting and the fatal lung damage...
...patients, none had a major lung-artery blockage while receiving phenindione. though three had embolisms (two of them fatal) after the drug was stopped. Among the untreated 150, no fewer than 15 deaths appeared to be solely or substantially attributable to traveling clots. Like all anticoagulants, phenindione must be given under the strictest medical supervision, usually in a hospital, with frequent laboratory tests to guard against the danger of uncontrollable bleeding, and some accidents or illnesses would preclude treatment. But with these precautions, the British method looks promising...
...breathing apparatus ("tracheobronchial tree") from the bodies of 402 men who died in Veterans Administration Hospital in East Orange and in eleven New York hospitals (mainly in nonindustrial towns to reduce bias that might result from air pollution). It turned out that 63 of the men had died of lung cancer and 339 from other causes, but the pathologists did not know this until after they had finished their findings. Each "tree" was cut into 208 portions and embedded in paraffin. Fifty-five of these portions, chosen for microscopic study, were then sliced three microns thick...
...pathologists were looking for changes in the cells, along a spectrum from normal through slightly abnormal to precancerous and finally cancerous. There were many abnormalities that the pathologists rated as probably too minor to be significant; also, many patients had died of pneumonia or other lung diseases. Even including these cases, the pathologists found atypical cells in only 3.8% of slides from nonsmokers and 10.9% of those from occasional cigarette smokers...
...startling rise in the chart for atypical cells: for men who smoked less than half a pack daily, it soared to 90.6% of the slides. In the half-pack to one-pack bracket, it was 97%; for one to two packs, 99.3%; more than two packs, 99.6%; and in lung cancer victims...