Word: lunged
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Dates: during 1990-1999
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...beliefs about size to other areas as well. Eisenmenger syndrome is a disease caused by a septal defect, or hole in the heart. As the condition progresses, fresh and deoxygenated blood begin to mix, with the latter seeping through to the body, causing pressure to build in the lungs and stretching the lung tissue. In the U.S., the defect is usually closed up right away, but in the developing world children often grow up with the hole. Until now, the solution was a heart/lung transplant, which has a high mortality rate. Batista suggests constricting the pulmonary artery to restrict...
These were not the first lethal side effects associated with Redux and fenfluramine. When Redux was approved, both Wyeth-Ayerst and the FDA already knew that the medication could lead to a potentially fatal lung condition known as primary pulmonary hypertension. But this problem seemed to affect only a small minority of users, and morbid obesity carries significant risks of its own: heart disease, diabetes, high blood pressure and stroke. On balance, the benefits seemed to outweigh the risks...
...capsules, they warned, were only a stopgap, not the final answer to obesity, which is still handled best by eating less and exercising more. They also pointed to unknown dangers from long-term use as well as evidence suggesting a risk of neurological damage and a rare but fatal lung disease...
Sources: Infectious Diseases Society of America; National Heart, Lung, and Blood Institute; Science...
...that weren't bad enough, physicians reported that a woman who had been taking fen-phen for less than a month died of primary pulmonary hypertension, a sometimes fatal lung condition already associated with Redux. And an article in the Journal of the American Medical Association last month confirmed earlier reports that both fen-phen and Redux can cause brain damage in lab animals...