Word: lungful
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...Those are only two drugs that keep EGF from doing its job. Glivec, which reversed Reiter's and Ferber's leukemia so dramatically, is another; so is Tarceva, a drug from OSI Pharmaceuticals in Uniondale, N.Y., which is showing promise against some lung tumors as well as head and neck cancers. Neither of these compounds keeps EGF from docking with cells; instead, each worms its way inside the cells, where it intercepts growth messages percolating in from the surface. Astra Zeneca, headquartered in London, is testing a similar compound, Iressa, against some lung, stomach and prostate cancers...
...proteasomes, which evidently play a role in giving cancer cells unnaturally long lives. The company is in Phase II trials with LDP341, a proteasome-inhibiting substance that is showing promise against multiple myeloma and chronic lymphocytic leukemia. Phase I studies on the top five solid tumors (breast, pancreatic, prostate, lung and colon) are under way, and at this point the inhibitor seems to be working?at least in mice...
...terminally ill patients, the best you can expect of the experimental drugs is to keep tumors from spreading. So researchers have begun to evaluate them in conjunction with traditional chemotherapy, radiation and surgery. So far, the results are promising. Preliminary trials involving patients with advanced non-small-cell lung cancer and kidney cancer suggest that the combination of angiogenesis inhibitors with standard therapy improves survival rates beyond those of either treatment alone...
...Courtesy of the National Heart, Lung and Blood Institute (NHLBI) >> Click here for additional information
...know, however, that preventing disease can be a lot easier and cheaper than trying to cure it. It was by studying the differences between people who get sick and people who don't--the branch of medical science known as epidemiology--that doctors discovered the link between smoking and lung cancer, between cholesterol and heart disease, between salt and high blood pressure. Epidemiology also led to the understanding that cooked tomatoes may help protect against prostate cancer, and that fruits and vegetables tend to stave off cancers of all sorts...