Word: lunging
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...could wish for, not least an unerring sense for where a defense was weak. A footballer among athletes, he was inventive, fearless and maybe the toughest of the tough. Born in Cessnock, New South Wales, to a coal-miner father, he played the 1997 grand final with a punctured lung amid reports that he was risking death. Yet he performed without a hint of apprehension, setting up the try that gave his beloved Newcastle their first premiership...
...conclusions had already provided the researchers at the National Heart, Lung and Blood Institute with hints that the heart-disease risk might apply unevenly, varying by age. And faced with growing concerns from menopausal women who depended on the hormones but were concerned about the danger, the investigators decided to take a second, closer look at the data. This time they teased the results apart more clearly into age groups. When they did, they found that the youngest of the women taking hormones weren't putting their hearts at risk so that there is a window of time, right around...
...change in managing cancer reflects a series of hard-won improvements in treatment - not, alas, for every form of cancer, but particularly for breast, colon, prostate and even lung. The gains include an explosion of new drugs that are more targeted and less toxic than old-school chemotherapeutic agents. In addition, new tests are beginning to help doctors match drugs more precisely to the genetic and molecular makeup of an individual tumor. Finally, there are remarkable advances in managing the side effects of treatment, which, in the past, could be as debilitating as cancer itself...
...treatment to the tumor. Oncotype Dx, introduced in 2004, looks at 21 genes in biopsied tissue to determine whether or not chemotherapy will be helpful for early breast cancer patients with recent diagnoses. At Duke University, molecular geneticist Joseph Nevins is testing a similar gene-based test for lung cancer. Researchers are aiming for tools that will tell them not only whether chemo is needed but also which specific drugs to use. Such a screen already exists for Herceptin, and many others are in development. Meantime, at the M.D. Anderson Cancer Center in Houston, Dr. Roy Herbst, chief of thoracic...
...Patients whose cancer moves into the bone tend to survive longer than those with metastases in the liver or lung. Russell says that she has a few patients who have survived 10 years with bone involvement, but this is extremely rare. The fact that Elizabeth Edwards relapsed just a little over two years after initial treatment is a bad sign, suggesting that her cancer is very aggressive. On the plus side, though, is that Edwards' disease is "low volume", according to her oncologist, Lisa Carey of Chapel Hill, N.C., meaning little tumor is present. Also favorable, says Russell, is that...