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...beliefs about size to other areas as well. Eisenmenger syndrome is a disease caused by a septal defect, or hole in the heart. As the condition progresses, fresh and deoxygenated blood begin to mix, with the latter seeping through to the body, causing pressure to build in the lungs and stretching the lung tissue. In the U.S., the defect is usually closed up right away, but in the developing world children often grow up with the hole. Until now, the solution was a heart/lung transplant, which has a high mortality rate. Batista suggests constricting the pulmonary artery to restrict...

Author: /time Magazine | Title: TOO BIG A HEART | 10/1/1997 | See Source »

...hepatitis C, according to the National Institutes of Health. The risk becomes greater as more units are transfused. "If you get 10 units of blood, the risk of HIV infection becomes 1 in 50,000," says George Nemo, leader of a group investigating transfusion medicine at the National Heart, Lung and Blood Institute. "If you're in an automobile accident, and you need 100 units, you're down to one in 5,000." Even when donor blood is deemed safe, if blood of the wrong group is transfused by mistake, recipients may suffer kidney failure, shock and clotting difficulties. Differences...

Author: /time Magazine | Title: BLOODLESS SURGERY | 10/1/1997 | See Source »

These were not the first lethal side effects associated with Redux and fenfluramine. When Redux was approved, both Wyeth-Ayerst and the FDA already knew that the medication could lead to a potentially fatal lung condition known as primary pulmonary hypertension. But this problem seemed to affect only a small minority of users, and morbid obesity carries significant risks of its own: heart disease, diabetes, high blood pressure and stroke. On balance, the benefits seemed to outweigh the risks...

Author: /time Magazine | Title: THE MOOD MOLECULE | 9/29/1997 | See Source »

...capsules, they warned, were only a stopgap, not the final answer to obesity, which is still handled best by eating less and exercising more. They also pointed to unknown dangers from long-term use as well as evidence suggesting a risk of neurological damage and a rare but fatal lung disease...

Author: /time Magazine | Title: WHO'S TO BLAME FOR REDUX AND FENFLURAMINE? | 9/29/1997 | See Source »

Sources: Infectious Diseases Society of America; National Heart, Lung, and Blood Institute; Science...

Author: /time Magazine | Title: Notebook: Sep. 29, 1997 | 9/29/1997 | See Source »

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