Word: lymphomas
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Researchers led by Louis Staudt, an oncologist at the National Cancer Institute, have been asking similar questions about lymphoma. In a paper published in the scientific journal Nature, they showed how lymphomas that look the same under the pathologist's microscope aren't necessarily identical. Staudt and his colleagues used DNA chips to see which genetic switches were being thrown in each of 40 different biopsy samples from lymphoma patients. By looking at specific genes involved in cell proliferation and immune-cell response, says Staudt, they determined that "two different kinds of tumors are hiding within the single diagnosis...
DIED. JEFF MACNELLY, 52, three-time Pulitzer prizewinning political cartoonist who created the comic strip Shoe, which is syndicated in 1,000 papers; of lymphoma; in Baltimore...
...After a Harvard career that spanned over 40 years, Pierce Professor of Philosophy Emeritus Burton S. Dreben '49 died of lymphoma July 11 in Boston...
...local entrepreneur and former member of Radcliffe College's Board of Trustees, Stanley Miller '52 died of lymphoma on Jan. 28 at his Newton home...
...years now, "smart" drugs have been the hottest trend in cancer treatment. They are designed to zero in on the proteins that nurture tumor cells. In the past year alone, the FDA has approved three such drugs (for non-Hodgkin's lymphoma, breast cancer and leukemia). And more are in the pipeline, because scientists are becoming increasingly skilled at designing drugs that target specific, critical molecular processes that tumor cells need to survive. Herceptin, for example, takes advantage of the fact that most breast-cancer cells overproduce a certain growth-factor protein; the drug preferentially seeks out tumor cells...