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Word: madrazo (lookup in dictionary) (lookup stats)
Dates: during 1980-1989
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Usage:

...transplant procedure was not without precedent. Beginning five years ago, doctors in Sweden tried similar surgery on four Parkinson's victims. They achieved only slight improvements that soon faded. Madrazo credits his team's success to modifications in surgical technique. The Swedes had transferred the adrenal tissue directly into a C-shaped structure in the middle of the brain called the caudate nucleus, where dopamine exerts its primary effects. The Mexicans, by contrast, used surgical staples to anchor the cells onto the exterior of the caudate, which is continually bathed in cerebrospinal fluid. This nourishing bath may have helped...

Author: /time Magazine | Title: Back To Normal: Hope for Parkinson's victims | 4/13/1987 | See Source »

...vital neurotransmitter that helps govern such voluntary actions as walking and speaking. As it happens, there is another site in the body, outside the brain, that produces substantial amounts of dopamine: the inner core of the adrenal glands. By transferring dopamine-producing adrenal cells into the brain, Dr. Ignacio Madrazo and his colleagues hoped to replenish the supply of this neurotransmitter and thus restore normal function...

Author: /time Magazine | Title: Back To Normal: Hope for Parkinson's victims | 4/13/1987 | See Source »

...Madrazo's amazement, the effects of the operations, performed in March and October of last year, became apparent in a matter of days. In the case of one of the two patients, he noted in the Journal, "functional recovery occurred on an almost daily basis." Both men are now leading normal lives, says Madrazo, and one has resumed managing his own farm. The loss of one adrenal gland has not presented any complications. Nor is rejection a problem, because the grafted tissue is the patient's own. Encouraged, Madrazo's team has tried the procedure on eight other patients. They...

Author: /time Magazine | Title: Back To Normal: Hope for Parkinson's victims | 4/13/1987 | See Source »

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