Word: manically
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Dates: during 2000-2009
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...direction in which neuroscience and psychiatry are headed. Once the art of the medical world, psychiatry is now the focus of the latest pharmaceutical technology and biomolecular manipulation. The laboratory where I've been working takes a genetic approach to analysis of bipolar affective disorder (BPAD, otherwise known as manic depression) and schizophrenia, each of which is estimated to affect 1 percent of the population worldwide. Deep within the bowels of NIMH, our effort to climb to the seat of the mind had been relegated to a lab in the windowless basement--we spend our days isolating and sequencing...
...notebooks are vital to understanding Graham's outlook on life. His half brother Phil married Katharine Meyer, whose father owned the Washington Post, and the couple were at the epicenter of the Washington social whirl of the 1960s. But at 49, Phil, a manic-depressive, killed himself. Bob Graham was 27 at the time. "Phil's legend was both inspiring and intimidating," says a person who knows Graham well and asks to remain anonymous. "After you see your brother commit suicide, one of the things you seek is control. No wild behavior, no profanity, no risk, loudness or recklessness...
...wrote to amuse ourselves," Leiber says. It shows in the manic energy and irrepressible good humor of their music. It's still hard not to laugh at the comic turns they wrote for the Coasters, such as Charlie Brown and Love Potion No. 9. Such story songs as Along Came Jones and Young Blood were inspired by Leiber's love of radio series like The Shadow. Their subjects ranged from knife fights and no-accounts to class clowns and the clap. That last can be found in what Leiber calls the "snide innuendo" of their hilarious Poison...
...first real comedy in three years, Carrey is all manic ingenuity. His eyebrows tango; he sports dry mouth and a milk mustache; he executes a quintuple spit take. It's not that he'll do anything to get a laugh. It's that he has the timing and gall to earn it--as in his metamorphosis from Charlie to Hank in one shot and with no special effects. You don't need ILM when you have...
...former costume assistant to Woody Allen, it's always the night of the living dead. The emotional zombies are disguised as parents and teachers. If they weren't so well behaved, they'd scream with perplexed rage. The only bright spot in this spiffy shtetl of depression is the manic, half-Italian Judy (The Sopranos' Edie Falco), and she's leaving town. Barbara Barrie, Bob Dishy and the late Madeline Kahn shine in a pristinely black-and-white portrait of domestic derangement. But the film is one-note; misery is the only game in town. Poor Jews, the movie says...