Word: manteno
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Dates: during 1940-1949
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When his super-centrifuge machine conked out and couldn't be repaired during the war, tousle-haired Biochemist John Vaichulis began looking around Illinois' Manteno State Mental Hospital for some other project to keep him busy. In one building on Manteno's grounds he found a group of patients who were never allowed to mix with other patients. They were the country's largest concentration of typhoid carriers, the backwash of a 1939 epidemic which swept Manteno, plus patients sent from other Illinois state hospitals to be isolated...
...research scientist when he was a kid in Chicago's Lithuanian slums 30 years ago, deciding to have a go at the tenacious typhoid bugs, teamed up in experiments with famed Illinois Physiologist Andrew C. Ivy (TIME, Jan. 13, 1947). There were 146 patients in Manteno's "Typhoid Hall" when Drs. Ivy and Vaichulis began treating them. By last week all but six had given repeated negative reactions to culture tests for typhoid; most had already been released as disinfected. The two doctors were ready to tell the world about two new treatments for typhoid carriers...
...antibiotic" which kills off the typhoid germs in two weeks to a month. Treatment No. 2, a combination of penicillin, three sulfa drugs (thiazole, diazine and merazine) plus alcohol and a dye called iodophthalein, injected in the patients' muscles or veins, works faster but it made 50% of Manteno's patients violently...
...Manteno. Others will have to wait at least a year until the treatments are ready for the market. Meanwhile, the two researchers are back in their laboratories, hoping to prove that their treatments will knock out other epidemic diseases such as cholera and dysentery...
Fleeting Hour. In Manteno, Ill., Edward W. Gorman bought a farm at 4:30 p.m., watched a tornado level...