Word: mapharsen
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Dates: during 1940-1940
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...ordinary fluid, but a sugary solution of mapharsen, one of the earlier of the 950-odd arsenic compounds invented by Paul Ehrlich. While the drug gently seeped into the patient's veins (two drops every three seconds), young Dr. William Leifer explained to the visitors one of the most remarkable advances in the treatment of syphilis since Chemist Ehrlich discovered arsphenamine...
...slowly dripping its weaker relative, mapharsen, into the bloodstream for eight hours a day, Drs. Hyman and Leifer and the third associate, Dr. Louis Chargin, eliminate the "shock" of relatively large injections, build up blood tolerance to huge concentrations of the essential arsenic. During a five-day treatment, a patient absorbs about two and a half gallons of mapharsen solution...
...doctors first tried neoarsphenamine in their Murphy drip, but found it "too dangerous." Mapharsen, which is less toxic, was discarded by Ehrlich because it was too unstable. But modern chemists have "set" the drug...
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