Word: maps
(lookup in dictionary)
(lookup stats)
Dates: all
Sort By: most recent first
(reverse)
Called the Connectivity Map, the development has already yielded insights into potential treatments for cancer and Alzheimer’s disease, the team reported in the Sept. 28 immediate early edition of Cancer Cell and the Sept. 29 issue of Science magazine...
...build the Connectivity Map, the scientists described the effects of different drugs and diseases using the language of “genomic signatures”—the set of genes that respond to a particular drug or disease with expression level changes. The scientists compiled the genomic signatures of more than 160 drugs and other biologically active compounds...
Lamb believes that the map can accelerate the search for new drugs to treat diseases with the support of the scientific community...
...Based on how successful the map seems to be with only 160 drugs, increasing the number of drugs for which we have the necessary information would increase the power of the map greatly,” Lamb said. “We already have the infrastructure in place to expand this resource quickly...
...Connectivity Map marks another step in an ongoing boom in biomedical genetics research. Earlier this month, a team including Will Parsons, a researcher at Johns Hopkins University and the National Cancer Institute, sequenced the genetic code for human breast and colon cancers...