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...good example of the interaction of research and clinical study is the work of Rawson's group and of Dr. L. D. Marinelli on the treatment of thyroid cancer with radioactive iodine. Since the thyroid gland eagerly absorbs iodine (which it uses to make a hormone), doctors have hoped that a cancerous thyroid would absorb radioactive iodine 131 in sufficient quantity to kill the unruly cells. Unfortunately, this effort was none too successful. The normal thyroid took up nearly all the iodine. The cancerous thyroid cells, particularly the metastases in distant parts of the body, took up so little...

Author: /time Magazine | Title: Medicine: Frontal Attack | 6/27/1949 | See Source »

Trained Metastases. Dr. Marinelli and his associates worked out a neat method of dealing with this difficulty. First they removed the patient's normal thyroid and with it the original cancer. This left the metastases which, they found, often consisted of cancer cells that retained faint remnants of the normal function of the thyroid. With the normal thyroid gone, the degenerate cells awoke and began to act like thyroids. Stimulated by the proper drugs, they began taking up iodine and making it into thyroid hormones. Then Dr. Marinelli gave radioactive iodine to the patient. The tumors, acting as pinchhitting...

Author: /time Magazine | Title: Medicine: Frontal Attack | 6/27/1949 | See Source »

...Monday, June 9, 1924, Dumini asked me for a car for three or four days. He told me it would be used by some of his friends and that I would be doing something which would give pleasure to Rossi [Fascist Press Chief] and Marinelli [then Economic Secretary of the Fascist party]. . . . I agreed that Dumini should use a car that I hired...

Author: /time Magazine | Title: ITALY: The Man Who Knew Too Much | 8/7/1944 | See Source »

Radioactive phosphorus, which Professor Lawrence puts up in liquid form, can be swallowed, in minute quantities, without danger. At Memorial. Drs. Kenney, Helen Quincy Woodard and Leonidas Marinelli gave small quantities of the stuff to patients who were to be operated on-and to a few about to die. When the tumors were removed, or the patients autopsied, the doctors calculated the amount of phosphorus absorbed by the cancerous tissue. They found that the chemical settled in the tumors, barely affected normal cells. Once in the tumors, the phosphorus acts like radium, burning out the rebel cells...

Author: /time Magazine | Title: Medicine: Phosphorus for Cancer | 12/16/1940 | See Source »

...State Department almost certainly established the identity of Mr. & Mrs. Donald L, Robinson, who recently disappeared in Moscow (TIME, Dec. 27), as a Mr. & Mrs. Adolph Arnold Rubens; further clarified the case by disclosing that New York's luckless County Clerk Albert Marinelli, who resigned from office month ago in the face of charges that members of his staff were ex-convicts, had issued the passports as a special kindness to a Mr. A, who had forwarded the applications as a political favor to a Mr. B, who obliged a Mr. C who had wanted to help...

Author: /time Magazine | Title: People, Jan. 10, 1938 | 1/10/1938 | See Source »

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