Word: marrow
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...Ernest McCulloch and James Till first proved the existence of stem cells, in the blood. These cells possess the ability to divide and create progeny - some of which will eventually expire, others that are self-renewing. The pair irradiated mice, destroying their immune cells. They then injected versatile bone-marrow cells into the animals' spleens and were surprised to see a ball of cells grow from each injection site. Each mass turned out to have emerged from a single stem cell, which in turn generated new blood cells...
...will use cells generated by Geron Corp. The approval marks the first time human stem cells, extracted and grown from embryos, will be transplanted into patients. Adult stem cells, which are present in many types of tissue, have been used in treatments for years - the most common being bone-marrow transplants in cancer care - but an embryonic study is a whole new thing. There's a good reason it's being greeted with so much excitement. (See the top 10 medical breakthroughs...
...study, released last week in “Nature Biotechnology,” found that some hematopoietic stem cells in bone marrow differentiate more slowly than others...
According to the study’s principal investigator, Harvard Medical School Professor Hanno R. Hock, such a discovery is “the holy grail of bone marrow transplant therapy...
These slower-dividing cells constitute a purer population of stem cells—one that could be useful in bone marrow transplant therapy, according to Harvard Medical School research fellow Adlen Foudi, one of the study’s lead co-authors...