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...Mari Kitahata, at the University of Washington, reports in the New England Journal of Medicine that HIV-positive patients enrolled in a nine-year study reduced their risk of dying as much as 94% by the trial's end if they began ART earlier, compared with patients who deferred treatment. "Our study adds to the weight of evidence accumulating that the balance between the potential benefit in survival of initiating therapy earlier outweighs the potential deleterious effects," says Kitahata, referring to concerns over the drugs' toxicity and possible long-term side effects...

Author: /time Magazine | Title: Study: Treatment for HIV Should Start Earlier | 4/2/2009 | See Source »

...objective is to standardize methods for validating genetic tests and guaranteeing accuracy and quality, says Mari Baker, CEO of California-based Navigenics. For now, all clinical labs, including those that conduct genetic tests, are regulated by the Centers for Medicare and Medicaid Services, which, under the federal Clinical Laboratory Improvement Amendments (CLIA), governs lab-personnel qualifications, quality-control procedures and proficiency testing. But critics argue that the law needs to be updated to include standards for genetic-testing labs. CLIA requires independent evaluations of labs' test-performance proficiency, for example, but genetic-testing labs are exempt from this rule, according...

Author: /time Magazine | Title: Should Genetic Tests Be Regulated? | 7/22/2008 | See Source »

...their doors to foreigners [March 17]. Although superficially Japan has the aura of being international, desperate measures are needed to educate the populace into accepting people from diverse national, racial and ethnic backgrounds. Such openness will be instrumental in pulling Japan away from its old legacy of national seclusion. Mari Oka, Tokyo

Author: /time Magazine | Title: Inbox | 4/3/2008 | See Source »

...Individual voices are hard to find, however. As dictated by the medium, the language of keitai shosetsu is simple and peppered with emoticons. Dialogue and description are sparse. Subject matter is predictable. "Keitai shosetsu are usually about love stories - often romantic relationships experienced by the target audience," says Mari Kuramachi, an editor at Starts. Typically, a heroine loses her first love (in K, the male love interest dies in an accident), then later struggles to find love again. Obstacles can be gritty - rape, drugs, accidental pregnancies and prostitution are all common - but they are invariably overcome, and traumatic events usually...

Author: /time Magazine | Title: Tone Language | 1/9/2008 | See Source »

...What part of your game would you like to change the most? -Mari Carmen Carmona, Antequera, Spain My serve. I'm always working on it harder, trying to get better. It's a technical problem, and it's difficult, but I am always working hard on it, every...

Author: /time Magazine | Title: 10 Questions for Rafael Nadal | 8/15/2007 | See Source »

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