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...reason may be that the field of gender-based medicine, which takes into account the differences between men and women in the diagnosis and treatment of disease, has been slow to catch on, especially in the pharmaceutical industry. Before the 1990s, women were largely excluded from clinical drug trials - an attempt to protect pregnant women from harm and avoid the potentially confounding effects of women's hormone fluctuations. Since then, as studies have actively recruited women, gender-based research has begun to reveal crucial information about how the development of diseases - such as heart disease, lung cancer and autoimmune disorders...

Author: /time Magazine | Title: Do Statins Work Equally for Men and Women? | 3/29/2010 | See Source »

Meanwhile, women on Crestor were more likely to develop diabetes compared with those getting a placebo - a result not seen in men. And because the trial lasted only 1.9 years on average, researchers say the full magnitude of the side effects may not have been captured...

Author: /time Magazine | Title: Do Statins Work Equally for Men and Women? | 3/29/2010 | See Source »

...Risk Profile, StupidWhy statins fail to show equal benefits for men and women is unclear, but one reason may be that women are simply at lower risk of heart disease than men. You would need a powerful treatment to lower an already low risk. Researchers also don't know why women are more likely than men to suffer side effects from statins and many other drugs but posit that lower body weight and hormonal fluctuations play a role. Biological explanations aside, the larger point is the same: with any treatment, the benefits should outweigh the risks...

Author: /time Magazine | Title: Do Statins Work Equally for Men and Women? | 3/29/2010 | See Source »

Many doctors may be so unfamiliar with the side effects of statins, says Golomb, that they deny their connection to the drugs. That may contribute to the underfiling of adverse-drug-reaction reports with the Food and Drug Administration...

Author: /time Magazine | Title: Do Statins Work Equally for Men and Women? | 3/29/2010 | See Source »

...terrorist up to the front doors of the Alfred P. Murrah Federal Building, they are taking a second look at people like Miller. It's not because Miller shows any signs of violent tendencies herself, but because she is one of the disseminators of a virulent antigovernment philosophy that may have helped plant thoughts of insurrection in someone else's head. Miller's own first thought upon hearing of the bombing was, "Oh, my gosh, I hope some idiot calling himself a patriot didn't do this." She admits that her own unarmed group, the Sons of Liberty, had attracted...

Author: /time Magazine | Title: The Threat from the Patriot Movement | 3/29/2010 | See Source »

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