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...results may finally give clinicians a bit of solid ground for counseling their patients. "We have not had real data to guide us," says Dr. Isabelle Bedrosian, the study's lead author and an assistant professor in the department of surgical oncology at MD Anderson. "We can't sit down with a woman and say, 'If you do this, this is your expected benefit.' And when we don't have those data, then biases become the big drivers of decisionmaking...
Part of the reason for the rise, say experts, has to do with improved genetic and imaging techniques that give women a lot of information about their tumors and the prognosis of their disease, which may sway them to take extreme measures to avoid recurrence...
...while the benefit may seem slight, Bedrosian notes that in cancer terms, any percentage boost in survival is meaningful, particularly to patients. And when women are facing the decision to lose a healthy breast, every piece of information counts. (See more about health care...
Whether the findings are sufficient to translate to the clinic, though, is another matter. Some experts are not convinced - yet - that the study results should be part of clinical decisionmaking, pointing out that many factors other than mastectomy may be driving the increase in survival. "Women who undergo a [preventive] mastectomy in the unaffected breast may be different from women who do not," says Dr. George Sledge, president-elect of the American Society of Clinical Oncology and a professor of medicine at Indiana University. "They may be overall healthier in that they see their physician more frequently, and their physicians...
...appears that UPS's ability to continually adjust to the economy and its ongoing evolution as a logistics provider has paid off. You may know it as an outfit that delivers the goods, but for UPS it's becoming less important that the folks in the brown trucks make the final handoff. Delivering a package efficiently is what it gets paid for. And the company is getting paid more often. "It's very rare to hear such bold statements from UPS management," says Helane Becker, transportation analyst for Jesup & Lamont Securities. "So we can take this to mean they truly...