Word: maying
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Research conducted by Eldo Kuzhikandathil, assistant professor of pharmacology at the University of Medicine and Dentistry of New Jersey, suggests that levamisole may indirectly increase the number of D1 dopamine receptors in the brain by affecting gene expression there. "Cocaine increases D1 expression," he says, "and this would probably accentuate that," which could enhance both highs and craving...
...boost heart rate - and studies of cocaine users show that they associate jumps in heart rate with getting high, spurring good feelings even before the drug hits the brain. A cut that accelerates heart rate might make them think they're getting the real thing. In the brain, levamisole may affect the same acetylcholine receptors activated by nicotine, another addictive drug that raises dopamine levels - which may be another clue to levamisole's lure. (See pictures of the antinarcotics police in Guinea-Bissau and Liberia...
...both physicians, the biggest mystery may be the power of cocaine addiction itself. Some of Graf's patients waited months before seeking help, as patches of painful, blackened skin continued to grow - and some continued to use cocaine despite learning that it caused their immune problems and that they could require plastic surgery to avoid permanent disfigurement. Zhu has treated several patients with life-threatening infections, some needing breathing tubes and intensive care. "It's quite sad - every time they use [cocaine], it happens. They wind up in the hospital for several weeks and almost die. But as soon...
...advantages, not surprisingly, were more profound for African Americans, who are more likely to develop high blood pressure and may be more sensitive to the hypertensive effects of salt than other ethnic groups, and for the elderly, since blood vessels stiffen with age, which can lead to higher blood pressure...
...enough to prevent you from reaching for the salt shaker at your next meal, but unfortunately, it may not be that easy to keep sodium levels in check. Almost 75% of the salt we consume each day comes from processed and prepared foods, such as breads, cereals and dairy products - sources we have very little control over, not to mention awareness of. (You can easily get 3 g of sodium in a single sandwich with two pieces of bread, some deli meat and cheese...