Word: maying
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...writers chafed at the limits this put on their reach, but also because it limited the advertising play. TimesSelect attracted 210,000 people, according to the newspaper, at about $50 a throw. As the recession set in and the Times' balance sheet began to look more reddish, executives may have come to mourn that lost $10 million...
...what can you really understand about the general population by studying a single family in the Netherlands? "When you have an isolated population, your findings may not be true of the population at large," acknowledges Dr. Ellen Schur, an internist at the University of Washington, who has also studied the link between migraines and depression. But her study of 1,064 pairs of female twins, published in the journal Headache in 2009, supports the idea of a common genetic link. Schur found that among her twin sets, migraine was inherited 44% of the time and depression 58%. When one sibling...
Researchers like Terwindt and Schur have already begun hunting for the exact genes that may underlie both migraine and depression - information that could lead to novel treatments for both conditions. But headache sufferers needn't wait around for such results. "If you have a headache that is disabling and comes and goes, the overwhelming odds are that it is migraine," says Dr. Stephen Silberstein, director of the Jefferson Headache Center in Philadelphia. Sufferers should consult their primary-care physicians for treatment, since there are already very effective treatments for migraines on the market today, and some medications (like the tricyclic...
Levamisole is cheap, widely available and seems to have the right look, taste and melting point to go unnoticed by cocaine users, which may alone account for its popularity. "Ease of availability seems likely to be important," says Reinarman. "Let's remember that producer countries are widely agrarian." Levamisole is used on farms, and its cost per gram is minimal...
...understanding of how levamisole affects the body, however, may better explain its explosive popularity. A 1998 paper found that levamisole relieved symptoms of heroin withdrawal in rats and also raised levels of various brain chemicals related to drug highs. "It may increase dopamine and by so doing may enhance cocaine effects," speculates Dr. Nora Volkow, director of the National Institute on Drug Abuse. (See 2009's best pictures...