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...genes. Then it seemed like simple fiction: while theoretically possible, gene therapy appeared unlikely to become a true therapeutic option, the field having suffered years of complications and high-profile setbacks. But over the past year, a series of small but intriguing advances has suggested that the technique may hold real future potential...

Author: /time Magazine | Title: Is Gene Therapy Finally Ready for Prime Time? | 11/27/2009 | See Source »

...findings suggest that when dopamine is present during an imagined event - that is, even when you're not actually experiencing it in person - it still influences how much pleasure the brain will expect from it in the future. Researchers think the extra shot of dopamine may aid learning - that is, it boosts your brain's learned association between pleasure and whatever experience you're thinking about at the time. Or perhaps, the authors speculate, the extra dopamine makes us simply want something more while we're imagining it. In other words, it would be useful to have...

Author: /time Magazine | Title: Can Dopamine Make Your Future Look Brighter? | 11/27/2009 | See Source »

...answer to the latter question is, yes. Although dopamine may be crucial to making decisions about future pleasure, too much of it might distort those decisions. A surplus of dopamine is at the root of addiction, for instance: Cocaine, for one, works in part by preventing brain cells from reabsorbing dopamine that the brain has released in connection with pleasurable sensations. And once the brain has learned to like cocaine, it causes all kinds of self-destructive behavior to satisfy its cravings...

Author: /time Magazine | Title: Can Dopamine Make Your Future Look Brighter? | 11/27/2009 | See Source »

...meetings. Between them, these 16 people are trying to rewrite the way the American financial industry does business - and, as a result, avoid another global financial meltdown. In theory, the process could succeed. "We have points of agreement," says one top GOP staffer. But he adds: "The working groups may not work because the issues are much too complex." (See award-winning pictures of the fallout from the financial meltdown...

Author: /time Magazine | Title: Senator Dodd's Bipartisan Push on Financial Reform | 11/27/2009 | See Source »

President Barack Obama recently sent a personal message to Pakistan's President Asif Ali Zardari, urging him to rally his compatriots to help the U.S. fight in Afghanistan. Obama's message may, however, have been sent to the wrong address, because it will likely take all of the the embattled Zardari's political energies - and then some - to simply remain in power. Already weighed down by the burdens of his deep unpopularity, the menace of burgeoning domestic extremism and a sour economy, Zardari faces a new crisis this Saturday with the expiration of an amnesty on corruption charges against...

Author: /time Magazine | Title: Corruption Charges Loom for Pakistan's Pro-U.S. President | 11/27/2009 | See Source »

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