Word: mckusick
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Dates: during 1960-1969
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...geneticists' meeting in Bar Harbor, Me., this week, Johns Hopkins University's Dr. Victor McKusick will report that his research team has now traced 150 U.S. families with a total of probably 250 dysautonomic children. All but two families are of Ashkenazic (North European Jewish) extraction, from which more than 98% of American Jews are descended. In those two families, the mother does not know of any Jewish ancestors. In Israel, the forebears of 30 such children were all Ashkenazim rather than Sephardim (Mediterranean Jews). How did dysautonomia become an Ashkenazic malady...
Billion to One. In roughly 1000 A.D., speculates Geneticist McKusick, a Rhineland Jew was hit in the gonads by either a cosmic ray or a ray from radioactive rock such as granite. By a billion-to-one chance, the ray damaged one of the genes that govern biochemical development in the embryo's nervous system, leaving a defect that impairs many automatic functions and sensory perception. While the victim's fertility was unimpaired, reasons McKusick, half of his many descendants carried the defective gene with them during a 13th century Jewish migration to Eastern Europe, the area that...
About one-fourth of all dysautonomic children die by age ten, Dr. McKusick reports. After that the death rate mounts steadily; the oldest patient on record is 36. The usual cause of death is the very problem that the infant encounters at first feeding: inhalation of food into the lungs, causing pneumonia, often coupled with heart failure. So far, the best palliative treatment for dysautonomia consists of using tranquilizers to help control the intense vomiting that characterizes the disorder. There is no cure...
...three-mile freshman run, Cornell's Gordon McKusick also set a new mark. His time of 14:46 was 12 seconds better than Messenger's year-old standard. Three other runners were clocked in better-than-record time. The best Harvard could do in that race was Doug Hardin's 35th place. The team panted into 11th place on the same kind of depth the varsity boasts. But it wasn't enough for Ivy League honors, which went to Cornell...
...League may produce the individual winner in the freshman race. Gordon McKusick of Cornell missed the course record by two seconds when he ran at Cortlandt before the Heps. He was not really challenged in that race, so he should be able to better the mark today...