Word: meaner
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Jose Luis Gonzalez, 60, has been called many things - almost none of them nice - in his 40 years working the streets of Lima, Peru's sprawling capital. "They call us vultures or scavengers most of the time, but sometimes they are meaner, saying we are thieves, criminals. It has never been easy work," he says. Gonzalez is one of an estimated 100,000 people in Peru who make a living diving through garbage to collect refuse - paper, metal, glass - that can be resold for a profit. It is a hardscrabble life, but one thing positive may now be handed...
...Main Street's Pullback For millions of Americans, the prospect of living within their means is a meaner one by the day. And it has consequences that are already showing in the bankruptcies of retailers such as Linens 'n Things, Mervyns, Steve & Barry's, Shoe Pavilion, Goody's and Sharper Image and in the possibility of poor holiday sales. The overleveraged consumer is the biggest economic problem the country faces, because debt has been the rocket fuel that has propelled growth for most of the past decade. Two-thirds of the $14 trillion U.S. economy is driven by consumer spending...
...much experience handling a crisis as McCain does, he's used his campaign itself as a stand-in, one long test of nerves. He resisted calls to take a hatchet to Hillary Clinton a year ago; as McCain gained ground in September, Democrats demanded that Obama get hotter and meaner. But he barely touched the thermostat. It's hard for McCain to charge that we don't know who Obama really is when he has been the most disciplined Democrat voters have seen in years...
...that mocks McCain's unfamiliarity with e-mail while featuring a Rubik's Cube, a prehistoric cell phone and other relics of 1982, the year of McCain's arrival in Congress. Campaign treasurer Martin Nesbitt says Obama is keenly aware of the pressure to "strike back and be meaner; fight fire with fire," but the candidate is not swayed by it. "He lets all the noise go on," Nesbitt says...
...immune factors, or correlates, that prevent infection, testing any vaccine candidate that functions by triggering immune defenses would be guesswork. That's why, Fauci says, he rejected the proposal to do a large trial, involving thousands of patients and numerous immune correlates. "What I will entertain is a leaner, meaner and smaller trial that precisely asks and answers, 'Does the vaccine work and is it successful in lowering viral load?'" Fauci says. "If it does, then we go back and start investing more money, people and samples to see if we can find the right immunological correlates. If it doesn...